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UTX Antibody
Catalog Number:OM294794
OM294794
Discount Price
OM294794-100ul
1~2 Week
100ul
OM294794-50ul
50ul
OM294794-20ul
20ul
1~2 Week
Product Profile
Product Name UTX Antibody
Antibody Type Primary Antibodies
Antigen Alias UTX, DKFZp686A03225, MGC141941, bA386N14.2, UTX, KABUK2
Product description UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.1) Hong, S., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (47), 18439-18444.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UTX.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
UTX antibody can be used for detection of UTX by ELISA at 1:312500. UTX antibody can be used for detection of UTX by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol KDM6A
Alternative Names UTX
DKFZp686A03225
MGC141941
bA386N14.2
UTX
KABUK2
Molecular Weight(MW) 154 kDa
Database Links
Entrez Gene 7403
Protein Accession NP_066963
Application

Application

Antibody used in WB on Human MCF7 cells at 0.2-1 ug/ml.
Positive Control 1) Cat. No. 1219 - MCF7 Cell Lysate
Application Notes UTX antibody can be used for detection of UTX by ELISA at 1:312500. UTX antibody can be used for detection of UTX by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store UTX antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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