Application
Immunohistochemistry of VKORC1 in human lung tissue with VKORC1 antibody at 2.5 μg/mL.Application
Immunohistochemistry of VKORC1 in human lung tissue with VKORC1 antibody at 2.5 μg/mL.Application
Immunohistochemistry of VKORC1 in human lung tissue with VKORC1 antibody at 2.5 μg/mL.| Product Name | VKORC1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | VKORC1 Antibody: VKOR, MST134, MST576, VKCFD2, EDTP308, IMAGE3455200, VKOR, MSTP134, MSTP576, UNQ308/PRO351, Vitamin K epoxide reductase complex subunit 1, Vitamin K1 2, 3-epoxide reductase subunit 1 |
| Product description | VKORC1 Antibody: Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form which is essential for blood clotting. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is VKORC1 that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance.1) Oldenburg J, Bevans CG, Muller CR, et al. Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycle. Antioxid. Redox Signal. 2006; 8:347-53. |
| Immunogen | VKORC1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human VKORC1. The immunogen is located within the first 50 amino acids of VKORC1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| VKORC1 antibody can be used for detection of VKORC1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 5 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | VKORC1 |
|---|---|
| Alternative Names | VKORC1 Antibody: VKOR MST134 MST576 VKCFD2 EDTP308 IMAGE3455200 VKOR MSTP134 MSTP576 UNQ308/PRO351 Vitamin K epoxide reductase complex subunit 1 Vitamin K1 2 3-epoxide reductase subunit 1 |
| Sequence Similarities | 2) Cat. No. 10-101 - Human Lung Tissue Slide |
Application
Immunohistochemistry of VKORC1 in human lung tissue with VKORC1 antibody at 2.5 μg/mL.
Application
Immunohistochemistry of VKORC1 in human lung tissue with VKORC1 antibody at 2.5 μg/mL.
Application
Immunohistochemistry of VKORC1 in human lung tissue with VKORC1 antibody at 2.5 μg/mL.| Positive Control | 1) Cat. No. 1203 - A549 Cell Lysate |
|---|---|
| Application Notes | VKORC1 antibody can be used for detection of VKORC1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | VKORC1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | VKORC1 Antibody is supplied in PBS containing 0.02% sodium azide. |
