Vacuolar protein sorting-associated protein 11 homolog, hVPS11, RING finger protein 108, VPS11, RNF108
Product description
Vesicle mediated protein sorting plays an important role
in segregation of intracellular molecules into distinct organelles.
Genetic studies in yeast have identified more than 40 vacuolar
protein sorting (VPS) genes involved in vesicle transport to
vacuoles. This gene encodes the human homolog of yeast class C
Vps11 protein. The mammalian class C Vps proteins are predominantly
associated with late endosomes/lysosomes, and like their yeast
counterparts, may mediate vesicle trafficking steps in the
endosome/lysosome pathway.1) Bailey, S.D., et al. Diabetes Care (2010) In press :
Immunogen
This VPS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 772-800 amino acids from the C-terminal region of human VPS11.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.