WD repeat domain phosphoinositide-interacting protein 4, WIPI-4, WD repeat-containing protein 45, WDR45, WDRX1, WDRXI4, WIPI4
Product description
This gene encodes a member of the WD repeat protein
family. WD repeats are minimally conserved regions of approximately
40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),
which may facilitate formation of heterotrimeric or multiprotein
complexes. Members of this family are involved in a variety of
cellular processes, including cell cycle progression, signal
transduction, apoptosis, and gene regulation. This gene has a
pseudogene at chromosome 4q31.3. Multiple alternatively spliced
transcript variants encoding distinct isoforms have been found for
this gene, but the biological validity and full-length nature of
some variants have not been determined.1) Proikas-Cezanne, T., et al. Oncogene 23(58):9314-9325(2004)
Immunogen
This WDR45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human WDR45.
Western Blot at 1:1000 dilution + human heart lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.