Application
Western blot analysis of WDR92 in human kidney tissue lysate with WDR92 antibody at (A) 1 and (B) 2 μg/mL.Application
Immunofluorescence of WDR92 in human testis tissue with WDR92 antibody at 20 μg/mL.Application
Immunohistochemistry of WDR92 in human testis tissue with WDR92 antibody at 10 μg/mL.| Product Name | WDR92 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WDR92 Antibody: WD repeat-containing protein 92, WD repeat-containing protein Monad |
| Product description | WDR92 Antibody: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR92, also known as monad, contains two WD40 repeats is widely expressed in human tissues, especially testis. Overexpression of this protein or its binding partner RNA polymerase II-associated protein 3 (RPAP3) potentiated apoptosis and caspase-3 activation induced by TNF-α and cycloheximide, suggesting that WDR92, together with RPAP3, may function as a novel modulator of apoptosis.1) Saeki M, Irie Y, Ni L, et al. Monad, a WD40 repeat protein, promotes apoptosis induced by TNF-alpha. Biochem. Biophys. Res. Commun.2006; 342:568-72. |
| Immunogen | WDR92 antibody was raised against a 21 amino acid synthetic peptide near the center of human WDR92. The immunogen is located within amino acids 140 - 190 of WDR92. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| WDR92 antibody can be used for detection of WDR92 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | WDR92 |
|---|---|
| Alternative Names | WDR92 Antibody: WD repeat-containing protein 92 WD repeat-containing protein Monad |
| Sequence Similarities | 2) Cat. No. 11-701 - Human Testis Tissue Slide |
Application
Western blot analysis of WDR92 in human kidney tissue lysate with WDR92 antibody at (A) 1 and (B) 2 μg/mL.
Application
Immunofluorescence of WDR92 in human testis tissue with WDR92 antibody at 20 μg/mL.
Application
Immunohistochemistry of WDR92 in human testis tissue with WDR92 antibody at 10 μg/mL.| Positive Control | 1) Cat. No. 1305 - Human Kidney Tissue Lysate |
|---|---|
| Application Notes | WDR92 antibody can be used for detection of WDR92 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | WDR92 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | WDR92 Antibody is supplied in PBS containing 0.02% sodium azide. |
