Application
Immunohistochemistry staining of WNK1 in testis tissue using WNK1 Antibody.| Product Name | WNK1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WNK1, Erythrocyte 65 kDa protein, HSAN2, KIAA0344, Kinase deficient protein, HWNK1, PHA2C, PRKWNK1, PSK, HSN2, KDP |
| Product description | WNK1, a WNK type protein kinase, contains a small N-terminal domain followed by a kinase domain and a long C-terminal tail. The protein is cytoplasmic and has been shown to regulate both the c-Jun N-terminal kinase pathway and the actin cytoskeleton in vitro. WNK1 has been identified as the gene mutant in pseudohypoaldosteronism type 2, also known as Gordon hyperkalemia-hypertension syndrome, which is a rare autosomal dominant form of volume-dependent, low-renin hypertension. Disease-causing mutations are large intronic deletions that increase WNK1 expression. At least two variants of WNK1 are produced by alternative splicing. |
| Immunogen | WNK1 antibody was raised against a peptide located near the internal domain of WNK1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| WNK1 antibody can be used in immunohistochemistry starting at 1:100, and immunofluorescence.: |
|
| Species Reactivity | GibbonGorillaHumanMonkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | WNK1 |
|---|---|
| Alternative Names | WNK1 Erythrocyte 65 kDa protein HSAN2 KIAA0344 Kinase deficient protein HWNK1 PHA2C PRKWNK1 PSK HSN2 KDP |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of WNK1 in testis tissue using WNK1 Antibody.| Application Notes | WNK1 antibody can be used in immunohistochemistry starting at 1:100, and immunofluorescence.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | WNK1 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
