The Wilms tumor suppressor gene WT1 appears to play a role
in both transcriptional and posttranscriptional regulation of
certain cellular genes. This gene encodes a WT1-associating
protein, which is a ubiquitously expressed nuclear protein. Like
WT1 protein, this protein is localized throughout the nucleoplasm
as well as in speckles and partially colocalizes with splicing
factors. Alternative splicing of this gene results in three
transcript variants, two of which encode the same isoform.1) Su, J., et al. Diabetes Res. Clin. Pract. 87(2):167-175(2010)
Immunogen
This WTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human WTAP.
Western blot analysis in Jurkat cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.