YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.1) Gronroos, E., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12165-12170.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YY1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCWB
YY1 antibody can be used for detection of YY1 by ELISA at 1:7812500. YY1 antibody can be used for detection of YY1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
YY1 antibody can be used for detection of YY1 by ELISA at 1:7812500. YY1 antibody can be used for detection of YY1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store YY1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.