Application
Western blot analysis of ZC3H12C in rat brain tissue lysate with ZC3H12C antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.Application
Immunofluorescence of ZC3H12C in human brain tissue with ZC3H12C antibody at 20 μg/mL.Application
Immunohistochemistry of ZC3H12C in human brain tissue with ZC3H12C antibody at 5 μg/mL.| Product Name | ZC3H12C Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ZC3H12C Antibody: MCPIP3, KIAA1726, MCPIP3, Probable ribonuclease ZC3H12C, MCP-induced protein 3 |
| Product description | ZC3H12C Antibody: ZC3H12C, also known as MCPIP3, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. Similar to ZC3H12A, ZC3H12C expression in macrophages is highly increased after treatment with lipopolysaccharide (LPS), suggesting it also may play a role in host immunity and inflammatory response.1) Zhou L, Azfer A, Niu J, et al. Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ. Res.2006; 98:1177-85. |
| Immunogen | ZC3H12C antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12C. The immunogen is located within the first 50 amino acids of ZC3H12C. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| ZC3H12C antibody can be used for detection of ZC3H12C by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZC3H12C |
|---|---|
| Alternative Names | ZC3H12C Antibody: MCPIP3 KIAA1726 MCPIP3 Probable ribonuclease ZC3H12C MCP-induced protein 3 |
| Sequence Similarities | 2) Cat. No. 10-301 - Human Brain Tissue Slide |
Application
Western blot analysis of ZC3H12C in rat brain tissue lysate with ZC3H12C antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Application
Immunofluorescence of ZC3H12C in human brain tissue with ZC3H12C antibody at 20 μg/mL.
Application
Immunohistochemistry of ZC3H12C in human brain tissue with ZC3H12C antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | ZC3H12C antibody can be used for detection of ZC3H12C by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | ZC3H12C antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ZC3H12C Antibody is supplied in PBS containing 0.02% sodium azide. |
