The FYVE domain mediates the recruitment of proteins
involved in membrane trafficking and cell signaling to
phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes.
This gene encodes a protein which contains two zinc-binding FYVE
domains in tandem. This protein displays a predominantly Golgi,
endoplasmic reticulum and vesicular distribution. Alternatively
spliced transcript variants have been found for this gene, and they
encode two isoforms with different sizes.1) Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Immunogen
This ZFYVE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the N-terminal region of human ZFYVE1.
Western blot analysis in human placenta tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.