Application
Western blot analysis of ZIMP7 in A20 cell lysate with ZIMP7 antibody at (A) 0.25 μg/ml and (B) 0.5 μg/mL.| Product Name | ZIMP7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | ZIMP7 Antibody: ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.1) Huang CY, Beliakoff J, Li X, et al. hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes. Mol. Endocrinol. 2005; 19:2915-29 |
| Immunogen | ZIMP7 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIMP7. The immunogen is located within amino acids 270 - 320 of ZIMP7. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ZIMP7 antibody can be used for detection of ZIMP7 by Western blot at 0.25 - 0.5 μg/mL. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZMIZ2 |
|---|---|
| Alternative Names | ZIMP7 Antibody: NET27 ZIMP7 hZIMP7 TRAFIP20 KIAA1886 HRIHFB2007 Zinc finger MIZ domain-containing protein 2 PIAS-like protein Zimp7 |
| Tissue Specificity | At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members. |
Application
Western blot analysis of ZIMP7 in A20 cell lysate with ZIMP7 antibody at (A) 0.25 μg/ml and (B) 0.5 μg/mL.| Positive Control | 1) Cat. No. 1288 - A20 Cell Lysate |
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| Application Notes | ZIMP7 antibody can be used for detection of ZIMP7 by Western blot at 0.25 - 0.5 μg/mL. |
| Form | Liquid |
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| Storage Instructions | ZIMP7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ZIMP7 Antibody is supplied in PBS containing 0.02% sodium azide. |
