Application
Western blot analysis of ZIP11 in mouse kidney tissue lysate with ZIP11 antibody at (A) 1 and (B) 2 μg/mL.Application
Immunohistochemistry of ZIP11 in mouse kidney tissue with ZIP11 antibody at 2.5 μg/mL.| Product Name | ZIP11 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | ZIP11 Antibody: ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist.1) Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch.2004; 447:796-800. |
| Immunogen | ZIP11 antibody was raised against a 15 amino acid synthetic peptide near the center of the human ZIP11. The immunogen is located within amino acids 130 - 180 of ZIP11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| ZIP11 antibody can be used for detection of ZIP11 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SLC39A11 |
|---|---|
| Alternative Names | ZIP11 Antibody: ZIP11 C17orf26 ZIP11 Zinc transporter ZIP11 Solute carrier family 39 member 11 ZIP-11 |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (86%) |
| Tissue Specificity | This antibody will not cross-react with the zinc transporter ZIP10. |
Application
Western blot analysis of ZIP11 in mouse kidney tissue lysate with ZIP11 antibody at (A) 1 and (B) 2 μg/mL.
Application
Immunohistochemistry of ZIP11 in mouse kidney tissue with ZIP11 antibody at 2.5 μg/mL.| Positive Control | 1) Cat. No. 1405 - Mouse Kidney Tissue Lysate |
|---|---|
| Application Notes | ZIP11 antibody can be used for detection of ZIP11 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | ZIP11 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ZIP11 Antibody is supplied in PBS containing 0.02% sodium azide. |
