The protein encoded by this gene contains a C2H2 zinc
finger, and has been shown to function as a transcriptional
repressor. The Kruppel-associated box (KRAB) domain of this protein
is found to be responsible for its transcriptional repression
activity. RING finger containing protein TIF1 was reported to
interact with the KRAB domain, and may serve as a mediator for the
repression activity of this protein.1) Lorenz, P., et al. Biol. Chem. 382(4):637-644(2001)
Immunogen
This ZNF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-148 amino acids from the N-terminal region of human ZNF10.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.