ZNF335 enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. ZNF335 may function by altering local chromatin structure.The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure.1) Garapaty, S., (2008) J. Biol. Chem. 283 (11), 6806-6816.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF335.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
ZNF335 antibody can be used for detection of ZNF335 by ELISA at 1:62500. ZNF335 antibody can be used for detection of ZNF335 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in WB on Human Brain at 0.2-1 ug/ml.
Positive Control
1) Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Application Notes
ZNF335 antibody can be used for detection of ZNF335 by ELISA at 1:62500. ZNF335 antibody can be used for detection of ZNF335 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ZNF335 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.