Application
Western blot analysis of ZNF346 in human kidney tissue lysate with ZNF346 antibody at (A) 1 and (B) 2 μg/mL.Application
Immunofluorescence of ZNF346 in human kidney tissue with ZNF346 antibody at 20 μg/mL.Application
Immunohistochemistry of ZNF346 (CT) in human kidney tissue with ZNF346 (CT) antibody at 5 μg/mL.| Product Name | ZNF346 (CT) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ZNF346 (CT) Antibody: JAZ, Zfp346, JAZ, Zinc finger protein 346, Just another zinc finger protein |
| Product description | ZNF346 (CT) Antibody: ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.1) Rosenfeld R and Margalit H. Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. J. Biomol. Struct. Dyn. 1993; 11:557-70. |
| Immunogen | ZNF346 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human ZNF346. The immunogen is located within the last 50 amino acids of ZNF346. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| ZNF346 antibody can be used for detection of ZNF346 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZNF346 |
|---|---|
| Alternative Names | ZNF346 (CT) Antibody: JAZ Zfp346 JAZ Zinc finger protein 346 Just another zinc finger protein |
| Sequence Similarities | 2) Cat. No. 10-401 - Human Kidney Tissue Slide |
| Tissue Specificity | ZNF346 antibody is predicted to not cross-react with other ZNF family members. Three isoforms of ZNF346 are known to exist; this antibody will recognize the two longest isoforms |
Application
Western blot analysis of ZNF346 in human kidney tissue lysate with ZNF346 antibody at (A) 1 and (B) 2 μg/mL.
Application
Immunofluorescence of ZNF346 in human kidney tissue with ZNF346 antibody at 20 μg/mL.
Application
Immunohistochemistry of ZNF346 (CT) in human kidney tissue with ZNF346 (CT) antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1305 - Human Kidney Tissue Lysate |
|---|---|
| Application Notes | ZNF346 antibody can be used for detection of ZNF346 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | ZNF346 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ZNF346 (CT) Antibody is supplied in PBS containing 0.02% sodium azide. |
