Application
Western blot analysis of ZNF687 in HeLa cell lysate with ZNF687 antibody at (A) 1 and (B) 2 μg/mL.Application
Immunofluorescence of ZNF687 in Jurkat cells with ZNF687 antibody at 10 μg/mL.| Product Name | ZNF687 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ZNF687 Antibody: KIAA1441, Zinc finger protein 687 |
| Product description | ZNF687 Antibody: The zinc finger protein 687 (ZNF687) was initially identified as a translocation partner gene with RUNX1 in patients with acute myeloid leukemia (AML). Little is known of the function of the ZNF687 protein, but it has been shown to weakly interact with the Ring1/Rnf2 RING finger protein member of the Polycomb group of proteins, suggesting it may be involved in the chromatin-modifying complexes essential for embryonic development and stem cell renewal. Other evidence suggests that ZNF687 may be part of a transcriptional network that also includes ZNF592 and ZMYMD8.1) Nguyen TT, Ma LN, Slovak ML, et al. Identification of novel Runx1 (AML1) translocation partner genes SH3D19, YTDf2, and ZNF687 in acute myeloid leukemia. Genes Chromo. Cancer 2006; 45:918-32. |
| Immunogen | ZNF687 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZNF687. The immunogen is located within amino acids 1160 - 1210 of ZNF687. |
| Modification | Acetylated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFWB |
| WB:1:500~1:2000 IF:1:100~1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZNF687 |
|---|---|
| Alternative Names | ZNF687 Antibody: KIAA1441 Zinc finger protein 687 |
| Molecular Weight(MW) | Predicted: 125 kDa Observed: 129 kDa |
| Tissue Specificity | ZNF687 antibody is human specific. At least three isoforms of ZNF687 are known to exist; this antibody will only detect the largest isoform. |
Application
Western blot analysis of ZNF687 in HeLa cell lysate with ZNF687 antibody at (A) 1 and (B) 2 μg/mL.
Application
Immunofluorescence of ZNF687 in Jurkat cells with ZNF687 antibody at 10 μg/mL.| Positive Control | HeLa Cell Lysate, Jurkat Cell Slide |
|---|---|
| Application Notes | WB:1:500~1:2000 IF:1:100~1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | ZNF687 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ZNF687 Antibody is supplied in PBS containing 0.02% sodium azide. |
