In a study identifying genes in rat that are upregulated
in response to nerve damage, a gene which is highly expressed in
ganglia and in the central nervous system was found. The protein
encoded by the rat gene contains both a zinc finger and a RING
finger motif and is localized in the endosome/lysosome compartment,
indicating that it may be involved in ubiquitin-mediated protein
modification. The protein encoded by this human gene is highly
similar in sequence to that encoded by the rat gene. [provided by
RefSeq].1) Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
Immunogen
This ZNRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the Central region of human ZNRF1.
Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.