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Transmembrane protein 2

Catalog Number:OM626674
OM626674
Discount Price
OM626674-100ul
1~2 Week
100ul
OM626674-50ul
50ul
OM626674-20ul
20ul
1~2 Week
Product Profile
Product Name Transmembrane protein 2
Antibody Type Primary Antibodies
Antigen Alias KIAA1412 antibody TMEM 2 antibody tmem2 antibody TMEM2_HUMAN antibody Transmembrane protein 2 antibody
Product description Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate.
Immunogen This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to transmembrane protein 2.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:1,000-1:2,000 IHC
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names KIAA1412 antibody TMEM 2 antibody tmem2 antibody TMEM2_HUMAN antibody Transmembrane protein 2 antibody
Molecular Weight(MW) 150 kDa
Cellular Localization Cell membrane. Membrane.
Database Links
SwissProt ID Q9UHN6 Q5FWI3
Application

Application

Fig1: Western blot analysis of TMEM2 on mouse heart tissue lysate using anti-TMEM2 antibody at 1/1,000 dilution.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-TMEM2 antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-TMEM2 antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-TMEM2 antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-TMEM2 antibody. Counter stained with hematoxylin.
Positive Control Mouse heart tissue, rat kidney tissue, human liver tissue, mouse liver tissue, mouse kidney tissue.
Application Notes WB:1:1,000-1:2,000 IHC
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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