Welcome to Omnimabs!
TEL: 02154156726 Info: info@Omnimabs.com

GPX4 [JU11-31]

Catalog Number:OM626858
OM626858
Discount Price
OM626858-100ul
1~2 Week
100ul
OM626858-50ul
50ul
OM626858-20ul
20ul
1~2 Week
Product Profile
Product Name GPX4 [JU11-31]
Antibody Type Primary Antibodies
Antigen Alias Glutathione peroxidase 4 antibody GPX 4 antibody GPX-4 antibody GPX4 antibody GPX4_HUMAN antibody GSHPx-4 antibody MCSP antibody mitochondrial antibody PHGPx antibody Phospholipid hydroperoxidase antibody Phospholipid hydroperoxide glutathione peroxidase antibody Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody snGPx antibody snPHGPx antibody Sperm nucleus glutathione peroxidase antibody
Product description Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1-8). GPx-1, Gpx-2 and Gpx-3 exist as homotetramers. Gpx-4 has a high tendancy to form high molecular weight oligomers.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIHC
WB:1:500-1:2,000
IHC:1:50-1:200
Species Reactivity HumanMouseRatZebra Fish
Concentration 1mg/ml
Target Information
Alternative Names Glutathione peroxidase 4 antibody GPX 4 antibody GPX-4 antibody GPX4 antibody GPX4_HUMAN antibody GSHPx-4 antibody MCSP antibody mitochondrial antibody PHGPx antibody Phospholipid hydroperoxidase antibody Phospholipid hydroperoxide glutathione peroxidase antibody Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody snGPx antibody snPHGPx antibody Sperm nucleus glutathione peroxidase antibody
Molecular Weight(MW) 22 kDa Clone number: JU11-31
Cellular Localization Mitochondrion.
Database Links
Application

Application

Fig1: Western blot analysis of GPX4 on different lysates using anti-GPX4 antibody at 1/500 dilution. Positive control: Lane 1: Rat liver Lane 2: Mouse kidney Lane 3: Human liver Lane 4: Jurkat

Application

Fig2: Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-GPX4 antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-GPX4 antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-GPX4 antibody. Counter stained with hematoxylin.

Application

Fig5: Western blot analysis of GPX4 on Zebrafish tissue lysates using anti-GPX4 antibody at 1/500 dilution.
Positive Control Rat liver tissue lysate, Jurkat, mouse kidney tissue lysate, human liver tissue lysate, Zebrafish tissue lysates, LOVO, MCF-7, PC-3M, rat epididymis tissue, human kidney tissue, mouse testis tissue.
Application Notes WB:1:500-1:2,000
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
validation
question title
question detaiil
Verification code