Compaction associated protein 1 antibody
Developmental pluripotency associated 3 antibody
Developmental pluripotency associated protein 3 antibody
Developmental pluripotency-associated protein 3 antibody
Dppa3 antibody
DPPA3_HUMAN antibody
PGC7 antibody
Stella related protein antibody
Stella-related protein antibody
Product description
Stella is a primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. It participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. It is important for the totipotent/pluripotent states continuing through preimplantation development.
Immunogen
peptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:2,000-1:5,000 IHC:1:100-1:200
Species Reactivity
HumanMouse
Concentration
1mg/ml
Target Information
Alternative Names
Compaction associated protein 1 antibody
Developmental pluripotency associated 3 antibody
Developmental pluripotency associated protein 3 antibody
Developmental pluripotency-associated protein 3 antibody
Dppa3 antibody
DPPA3_HUMAN antibody
PGC7 antibody
Stella related protein antibody
Stella-related protein antibody