Application
Fig1: Flow cytometric analysis of 293 cells with TCF3 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.| Product Name | TCF3 [SY0258] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AGM8 antibody bHLHb21 antibody Class B basic helix-loop-helix protein 21 antibody E12 antibody E2A antibody E2A immunoglobulin enhancer binding factors E12/E47 antibody E47 antibody Helix loop helix protein HE47 antibody Immunoglobulin enhancer-binding factor E12/E47 antibody Immunoglobulin transcription factor 1 antibody ITF1 antibody Kappa-E2-binding factor antibody MGC129647 antibody MGC129648 antibody Negative vitamin D response element binding protein antibody NOL1-TCF3 fusion antibody TCF-3 antibody Tcf3 antibody TFE2_HUMAN antibody transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) antibody Transcription factor 3 antibody transcription factor 3 variant 3 antibody Transcription factor E2-alpha antibody Transcription factor ITF-1 antibody VDIR antibody VDR interacting repressor antibody vitamin D receptor-interacting repressor antibody |
| Product description | Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development include Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and heterooligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBFC |
| WB:1:1,000 FC:1:50-1:100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | AGM8 antibody bHLHb21 antibody Class B basic helix-loop-helix protein 21 antibody E12 antibody E2A antibody E2A immunoglobulin enhancer binding factors E12/E47 antibody E47 antibody Helix loop helix protein HE47 antibody Immunoglobulin enhancer-binding factor E12/E47 antibody Immunoglobulin transcription factor 1 antibody ITF1 antibody Kappa-E2-binding factor antibody MGC129647 antibody MGC129648 antibody Negative vitamin D response element binding protein antibody NOL1-TCF3 fusion antibody TCF-3 antibody Tcf3 antibody TFE2_HUMAN antibody transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) antibody Transcription factor 3 antibody transcription factor 3 variant 3 antibody Transcription factor E2-alpha antibody Transcription factor ITF-1 antibody VDIR antibody VDR interacting repressor antibody vitamin D receptor-interacting repressor antibody |
|---|---|
| Molecular Weight(MW) | 67 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P15923 |
|---|
Application
Fig1: Flow cytometric analysis of 293 cells with TCF3 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.| Positive Control | 293 |
|---|---|
| Application Notes | WB:1:1,000 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
