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STAT6 [SY02-72]

Catalog Number:OM627008
OM627008
Discount Price
OM627008-100ul
1~2 Week
100ul
OM627008-50ul
50ul
OM627008-20ul
20ul
1~2 Week
Product Profile
Product Name STAT6 [SY02-72]
Antibody Type Primary Antibodies
Antigen Alias 12S1644 antibody D12S1644 antibody IL 4 STAT antibody IL-4 Stat antibody IL4 STAT antibody Interleukin 4 Induced antibody Interleukin 4 Induced Transcription Factor IL4 STAT antibody Signal transducer and activator of transcription 6 antibody Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced antibody Signal Transducer And Activator Of Transcription 6 Nirs Variant 1 antibody Signal transducer and activator of transcription 6, interleukin 4 induced antibody STAT 6 antibody STAT interleukin4 induced antibody STAT, interleukin4 induced antibody Stat6 antibody STAT6_HUMAN antibody STAT6B antibody STAT6C antibody Transcription factor IL 4 STAT antibody
Product description nated Stats (signal transducers and activators of transcription). The first members of this family to be described include Stat1α p91, Stat1β p84 (a form of p91 that lacks 38 COOH-terminal amino acids) and Stat2 p113. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Stat3, which becomes activated in response to epidermal growth factor (EGF) and interleukin-6 (IL-6), but not interferon-? (IFN-?) or Stat4, is an additional member of this family. It has been suggested that the phosphorylated forms of both Stat3 and Stat4 form homodimers as well as heterodimers with the other members of the Stat family, and that differential activation of different Stat proteins in response to different ligands should help to explain specificity in nuclear signaling from the cell surface. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Other members of the Stat family include Stat5, which has been shown to be activated by prolactin and by IL-3, and Stat6 (also designated IL-4 Stat), which is involved in IL-4-activated signaling pathways.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICC/IFIHCIP
WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Alternative Names 12S1644 antibody D12S1644 antibody IL 4 STAT antibody IL-4 Stat antibody IL4 STAT antibody Interleukin 4 Induced antibody Interleukin 4 Induced Transcription Factor IL4 STAT antibody Signal transducer and activator of transcription 6 antibody Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced antibody Signal Transducer And Activator Of Transcription 6 Nirs Variant 1 antibody Signal transducer and activator of transcription 6
interleukin 4 induced antibody STAT 6 antibody STAT interleukin4 induced antibody STAT
interleukin4 induced antibody Stat6 antibody STAT6_HUMAN antibody STAT6B antibody STAT6C antibody Transcription factor IL 4 STAT antibody
Molecular Weight(MW) 94 kDa
Cellular Localization Cytoplasm, Nucleus.
Database Links
SwissProt ID P42226 P52633
Application

Application

Fig1: Western blot analysis of STAT6 on different lysates using anti-STAT6 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: Raji

Application

Fig2: ICC staining STAT6 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: ICC staining STAT6 in AGS cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig4: ICC staining STAT6 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-STAT6 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-STAT6 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-STAT6 antibody. Counter stained with hematoxylin.

Application

Fig8: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-STAT6 antibody. Counter stained with hematoxylin.

Application

Fig9: Immunohistochemical analysis of paraffin-embedded mouse stomach tissue using anti-STAT6 antibody. Counter stained with hematoxylin.
Positive Control Raji, AGS, Hela, NIH/3T3, human tonsil tissue, mouse stomach tissue, human breast carcinoma tissue, mouse stomach tissue, human kidney tissue, mouse lung tissue.
Application Notes WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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