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Stathmin 1 [SS0453]

Catalog Number:OM627095
OM627095
Discount Price
OM627095-100ul
1~2 Week
100ul
OM627095-50ul
50ul
OM627095-20ul
20ul
1~2 Week
Product Profile
Product Name Stathmin 1 [SS0453]
Antibody Type Primary Antibodies
Antigen Alias C1orf215 antibody Lag antibody LAP 18 antibody LAP18 antibody Leukemia associated phosphoprotein p18 antibody Leukemia-associated phosphoprotein p18 antibody Metablastin antibody Oncoprotein 18 antibody OP 18 antibody Op18 antibody p18 antibody p19 antibody Phosphoprotein 19 antibody Phosphoprotein p19 antibody pp17 antibody pp19 antibody PR22 antibody Pr22 protein antibody Prosolin antibody Protein Pr22 antibody SMN antibody Stathmin antibody Stathmin1 antibody STMN 1 antibody Stmn1 antibody STMN1_HUMAN antibody
Product description Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, tubulin-associated, intracellular phosphoprotein . Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICCIHCIPFC
WB:1:1,000-1:2,000
ICC:1:100-1:500
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names C1orf215 antibody Lag antibody LAP 18 antibody LAP18 antibody Leukemia associated phosphoprotein p18 antibody Leukemia-associated phosphoprotein p18 antibody Metablastin antibody Oncoprotein 18 antibody OP 18 antibody Op18 antibody p18 antibody p19 antibody Phosphoprotein 19 antibody Phosphoprotein p19 antibody pp17 antibody pp19 antibody PR22 antibody Pr22 protein antibody Prosolin antibody Protein Pr22 antibody SMN antibody Stathmin antibody Stathmin1 antibody STMN 1 antibody Stmn1 antibody STMN1_HUMAN antibody
Molecular Weight(MW) 18 kDa
Cellular Localization Cytoplasm
Database Links
Application

Application

Fig1: ICC staining Stathmin 1 in PC-12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig2: ICC staining Stathmin 1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: ICC staining Stathmin 1 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Stathmin 1 antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Stathmin 1 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded mouse spinal cord tissue using anti-Stathmin 1 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Stathmin 1 antibody. Counter stained with hematoxylin.

Application

Fig8: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Stathmin 1 antibody. Counter stained with hematoxylin.

Application

Fig9: Flow cytometric analysis of Hela cells with Stathmin 1 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Positive Control PC-12, SH-SY-5Y, Hela, human tonsil tissue, human breast carcinoma tissue, mouse testis tissue, mouse spinal cord tissue, mouse brain tissue.
Application Notes WB:1:1,000-1:2,000
ICC:1:100-1:500
IHC:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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