Application
Fig1: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-c-Kit antibody. Counter stained with hematoxylin.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-c-Kit antibody. Counter stained with hematoxylin.| Product Name | c-Kit [ST04-99] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C Kit antibody c-Kit antibody c-Kit Ligand antibody CD117 antibody Kit antibody Kit Ligand antibody KIT oncogene antibody KIT proto oncogene receptor tyrosine kinase antibody KIT_HUMAN antibody Mast cell growth factor receptor antibody Mast/stem cell growth factor receptor Kit antibody MGF antibody p145 c-kit antibody PBT antibody Piebald trait protein antibody Proto oncogene c Kit antibody Proto oncogene tyrosine protein kinase Kit antibody Proto-oncogene c-Kit antibody SCF Receptor antibody SCFR antibody soluble KIT variant 1 antibody Steel Factor Receptor antibody Stem cell factor receptor antibody tyrosine protein kinase Kit antibody Tyrosine-protein kinase Kit antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody |
| Product description | The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | C Kit antibody c-Kit antibody c-Kit Ligand antibody CD117 antibody Kit antibody Kit Ligand antibody KIT oncogene antibody KIT proto oncogene receptor tyrosine kinase antibody KIT_HUMAN antibody Mast cell growth factor receptor antibody Mast/stem cell growth factor receptor Kit antibody MGF antibody p145 c-kit antibody PBT antibody Piebald trait protein antibody Proto oncogene c Kit antibody Proto oncogene tyrosine protein kinase Kit antibody Proto-oncogene c-Kit antibody SCF Receptor antibody SCFR antibody soluble KIT variant 1 antibody Steel Factor Receptor antibody Stem cell factor receptor antibody tyrosine protein kinase Kit antibody Tyrosine-protein kinase Kit antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody |
|---|---|
| Molecular Weight(MW) | 110 kDa |
| Cellular Localization | Cell membrane, Cytoplasm. |
| SwissProt ID | P10721 |
|---|
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-c-Kit antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-c-Kit antibody. Counter stained with hematoxylin.| Positive Control | Human breast carcinoma tissue, human spleen tissue. |
|---|---|
| Application Notes | WB:1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
