Application
Fig1: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-TPH1 antibody. Counter stained with hematoxylin.Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue using anti-TPH1 antibody. Counter stained with hematoxylin.Application
Fig3: Flow cytometric analysis of Hela cells with TPH1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.| Product Name | Tryptophan Hydroxylase 1 (TPH1) [SC53-07] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Indoleacetic acid 5 hydroxylase antibody L tryptophan hydroxylase antibody MGC119994 antibody TPH 1 antibody TPH antibody TPH1 antibody TPH1_HUMAN antibody TPRH antibody TRPH antibody Tryptophan 5 hydroxylase 1 antibody Tryptophan 5 monooxygenase 1 antibody Tryptophan 5 monooxygenase antibody Tryptophan 5-hydroxylase 1 antibody Tryptophan 5-monooxygenase 1 antibody Tryptophan hydroxylase 1 antibody |
| Product description | biosynthesis of serotonin in the central nervous system and melatonin in the pineal gland. Alteration of TPH function may be a key factor in the pathology of several neuropsychiatric disorders associated with serotonin, including depression, aggression, alcoholism and schizophrenia. For instance, L-DOPA, which is used as a common therapy for Parkinson’s disease (PD) patients, inhibits TPH function, which subsequently, is thought to contribute to the onset of depression in PD patients. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICC/IFIHCIPFC |
| WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Indoleacetic acid 5 hydroxylase antibody L tryptophan hydroxylase antibody MGC119994 antibody TPH 1 antibody TPH antibody TPH1 antibody TPH1_HUMAN antibody TPRH antibody TRPH antibody Tryptophan 5 hydroxylase 1 antibody Tryptophan 5 monooxygenase 1 antibody Tryptophan 5 monooxygenase antibody Tryptophan 5-hydroxylase 1 antibody Tryptophan 5-monooxygenase 1 antibody Tryptophan hydroxylase 1 antibody |
|---|---|
| Molecular Weight(MW) | 51 kDa |
| Cellular Localization | Cytoplasm. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-TPH1 antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue using anti-TPH1 antibody. Counter stained with hematoxylin.
Application
Fig3: Flow cytometric analysis of Hela cells with TPH1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.| Positive Control | Rat brain tissue, mouse cerebellum tissue. |
|---|---|
| Application Notes | WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
