Application
Fig1: Western blot analysis of RPA32/RPA2 (phospho T21) on Hela cells lysates using anti-RPA32/RPA2 (phospho T21) antibody at 1/1,000 dilution.| Product Name | RPA32/RPA2 (phospho T21) [SN06-36] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 60S acidic ribosomal protein P1 antibody AA409079 antibody AI325195 antibody AU020965 antibody ik:tdsubc_2g1 antibody M(2)21C antibody MGC137236 antibody OTTHUMP00000004008 antibody p32 antibody p34 antibody RCJMB04_6d17 replication protein A2, 32kDa antibody REPA2 antibody Replication factor A protein 2 antibody Replication protein A 32 kDa subunit antibody Replication protein A 32kDa subunit antibody Replication protein A 34 kDa subunit antibody Replication protein A antibody Replication Protein A2 (32kDa) antibody Replication protein A2 antibody Replication protein A2, 32kDa antibody RF-A protein 2 antibody Rf-A2 antibody RFA antibody RFA2_HUMAN antibody RP-A p32 antibody RP-A p34 antibody RP21C antibody RPA 2 antibody RPA 32 antibody RPA antibody Rpa2 antibody RPA32 antibody RPA34 antibody RpLP1 antibody RpP2 antibody xx:tdsubc_2g1 antibody zgc:109822 antibody |
| Product description | The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses. Replication protein A (RPA), a highly conserved eukaryotic protein, is a heterotrimeric SSB. RPA plays an important role in DNA replication, recombination and repair. The binding of human RPA (hRPA) to DNA involves molecular polarity in which initial hRPA binding occurs on the 5' side of a ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA. RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The C-terminus of RPA 32 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, RPA 32 binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA 32 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3. |
| Immunogen | recombinant protein |
| Modification | p-T21 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIP |
| WB:1:1,000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 60S acidic ribosomal protein P1 antibody
AA409079 antibody
AI325195 antibody
AU020965 antibody
ik:tdsubc_2g1 antibody
M(2)21C antibody
MGC137236 antibody
OTTHUMP00000004008 antibody
p32 antibody
p34 antibody
RCJMB04_6d17 replication protein A2 32kDa antibody REPA2 antibody Replication factor A protein 2 antibody Replication protein A 32 kDa subunit antibody Replication protein A 32kDa subunit antibody Replication protein A 34 kDa subunit antibody Replication protein A antibody Replication Protein A2 (32kDa) antibody Replication protein A2 antibody Replication protein A2 32kDa antibody RF-A protein 2 antibody Rf-A2 antibody RFA antibody RFA2_HUMAN antibody RP-A p32 antibody RP-A p34 antibody RP21C antibody RPA 2 antibody RPA 32 antibody RPA antibody Rpa2 antibody RPA32 antibody RPA34 antibody RpLP1 antibody RpP2 antibody xx:tdsubc_2g1 antibody zgc:109822 antibody |
|---|---|
| Molecular Weight(MW) | 32 kDa |
| Cellular Localization | Nucleus. |
Application
Fig1: Western blot analysis of RPA32/RPA2 (phospho T21) on Hela cells lysates using anti-RPA32/RPA2 (phospho T21) antibody at 1/1,000 dilution.| Positive Control | Hela. |
|---|---|
| Application Notes | WB:1:1,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
