Application
Fig1: Western blot analysis of Estrogen Receptor beta on 293T cells lysates using anti-Estrogen Receptor beta antibody at 1/1,000 dilution.| Product Name | Estrogen Receptor beta [JJ09-02] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ER BETA antibody ER-beta antibody Erb antibody ESR B antibody ESR BETA antibody ESR2 antibody ESR2_HUMAN antibody ESRB antibody ESTRB antibody estrogen nuclear receptor beta variant a antibody estrogen nuclear receptor beta variant b antibody estrogen receptor 2 (ER beta) antibody Estrogen receptor 2 antibody estrogen receptor beta 4 antibody Estrogen receptor beta antibody NR3A2 antibody Nuclear receptor subfamily 3 group A member 2 antibody |
| Product description | Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functional characteristics. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB |
| WB:1:1,000-1:2,000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ER BETA antibody ER-beta antibody Erb antibody ESR B antibody ESR BETA antibody ESR2 antibody ESR2_HUMAN antibody ESRB antibody ESTRB antibody estrogen nuclear receptor beta variant a antibody estrogen nuclear receptor beta variant b antibody estrogen receptor 2 (ER beta) antibody Estrogen receptor 2 antibody estrogen receptor beta 4 antibody Estrogen receptor beta antibody NR3A2 antibody Nuclear receptor subfamily 3 group A member 2 antibody |
|---|---|
| Molecular Weight(MW) | 59 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q92731 |
|---|
Application
Fig1: Western blot analysis of Estrogen Receptor beta on 293T cells lysates using anti-Estrogen Receptor beta antibody at 1/1,000 dilution.| Positive Control | 293T, human breast carcinoma tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
