Application
Fig1: Western blot analysis of LAMP1 on different lysates using anti-LAMP1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: JurkatApplication
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LAMP1 antibody. Counter stained with hematoxylin.| Product Name | LAMP1 [JJ0940] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD107 antigen like family member A antibody CD107 antigen-like family member A antibody CD107a antibody CD107a antigen antibody LAMP 1 antibody LAMP-1 antibody LAMP1 antibody LAMP1_HUMAN antibody LAMPA antibody LGP120 antibody lgpA antibody Lysosomal membrane glycoprotein 120KD antibody Lysosomal Associated Membrane Protein 1 antibody Lysosome associated membrane glycoprotein 1 antibody Lysosome-associated membrane glycoprotein 1 antibody Lysosome-associated membrane protein 1 antibody OTTHUMP00000040663 antibody |
| Product description | Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107a) and LAMP-2 (also designated CD107b) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans-Golgi network and are transported intracellularly via a pathway that is distinct from the Clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of Thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000-1:2,000 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CD107 antigen like family member A antibody CD107 antigen-like family member A antibody CD107a antibody CD107a antigen antibody LAMP 1 antibody LAMP-1 antibody LAMP1 antibody LAMP1_HUMAN antibody LAMPA antibody LGP120 antibody lgpA antibody Lysosomal membrane glycoprotein 120KD antibody Lysosomal Associated Membrane Protein 1 antibody Lysosome associated membrane glycoprotein 1 antibody Lysosome-associated membrane glycoprotein 1 antibody Lysosome-associated membrane protein 1 antibody OTTHUMP00000040663 antibody |
|---|---|
| Molecular Weight(MW) | 120 kDa |
| Cellular Localization | Cell membrane, Endosome membrane, Lysosome membrane, Late endosome. |
| SwissProt ID | P11279 |
|---|
Application
Fig1: Western blot analysis of LAMP1 on different lysates using anti-LAMP1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: Jurkat
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LAMP1 antibody. Counter stained with hematoxylin.| Positive Control | Jurkat, Hela, human kidney tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
