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S100A10 [JF0987]

Catalog Number:OM628217
OM628217
Discount Price
OM628217-100ul
1~2 Week
100ul
OM628217-50ul
50ul
OM628217-20ul
20ul
1~2 Week
Product Profile
Product Name S100A10 [JF0987]
Antibody Type Primary Antibodies
Antigen Alias 42C antibody AA409961 antibody AL024248 antibody Annexin II ligand antibody Annexin II ligand, calpactin I, light polypeptide antibody Annexin II tetramer (AIIt) p11 subunit antibody Annexin II, light chain antibody ANX2L antibody ANX2LG antibody Ca[1] antibody CAL12 antibody CAL1L antibody Calpactin I light chain antibody Calpactin I, p11 subunit antibody Calpactin-1 light chain antibody Cellular ligand of annexin II antibody CLP11 antibody GP11 antibody MGC111133 antibody Nerve growth factor-induced protein 42C antibody OTTHUMP00000015269 antibody OTTHUMP00000015270 antibody p10 antibody p10 protein antibody p11 antibody Protein S100 A10 antibody Protein S100-A10 antibody S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) antibody S100 calcium binding protein A10 (calpactin) antibody S100 calcium binding protein A10 antibody S100 calcium-binding protein A10 antibody S100a10 antibody S10AA_HUMAN antibody
Product description The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIHC
WB:1:1,000-1:2,000
IHC:1:50-1:200
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Alternative Names 42C antibody AA409961 antibody AL024248 antibody Annexin II ligand antibody Annexin II ligand
calpactin I
light polypeptide antibody Annexin II tetramer (AIIt) p11 subunit antibody Annexin II
light chain antibody ANX2L antibody ANX2LG antibody Ca[1] antibody CAL12 antibody CAL1L antibody Calpactin I light chain antibody Calpactin I
p11 subunit antibody Calpactin-1 light chain antibody Cellular ligand of annexin II antibody CLP11 antibody GP11 antibody MGC111133 antibody Nerve growth factor-induced protein 42C antibody OTTHUMP00000015269 antibody OTTHUMP00000015270 antibody p10 antibody p10 protein antibody p11 antibody Protein S100 A10 antibody Protein S100-A10 antibody S100 calcium binding protein A10 (annexin II ligand
calpactin I
light polypeptide (p11)) antibody S100 calcium binding protein A10 (calpactin) antibody S100 calcium binding protein A10 antibody S100 calcium-binding protein A10 antibody S100a10 antibody S10AA_HUMAN antibody
Molecular Weight(MW) 11 kDa
Cellular Localization Extracellular exosome.
Database Links
SwissProt ID P60903 P08207
Application

Application

Fig1: Western blot analysis of S100A10 on human lung lysates using anti-S100A10 antibody at 1/1,000 dilution.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-S100A10 antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-S100A10 antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human gastric carcinoma tissue using anti-S100A10 antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-S100A10 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
Positive Control Human lung tissue, human colon cancer tissue, human kidney tissue, human gastric carcinoma tissue, mouse colon tissue, mouse kidney tissue.
Application Notes WB:1:1,000-1:2,000
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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