Application
Fig1: Western blot analysis of PPAR gamma on PC-12 cells lysates using anti-PPAR gamma antibody at 1/1,000 dilution.| Product Name | PPAR gamma [JF101-4] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CIMT1 antibody GLM1 antibody NR1C3 antibody Nuclear receptor subfamily 1 group C member 3 antibody OTTHUMP00000185032 antibody OTTHUMP00000185036 antibody Peroxisome proliferator activated nuclear receptor gamma variant 1 antibody Peroxisome proliferator activated receptor gamma 1 antibody Peroxisome Proliferator Activated Receptor gamma antibody Peroxisome proliferator-activated receptor gamma antibody PPAR gamma antibody PPAR-gamma antibody PPARG antibody PPARG_HUMAN antibody PPARG1 antibody PPARG2 antibody PPARgamma antibody |
| Product description | Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor subfamily of transcription factors. PPARs form heterodimers with retinoid X receptors (RXRs). These heterodimers regulate transcription of genes involved in insulin action, adipocyte differentiation, lipid metabolism and inflammation. PPARγ is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPARγ activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPARγ may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. A Pro12Ala polymorphism of the PPARγ2 gene has been reported to reduce transactivation activity in vitro. This substitution may affect the immune response to ox-LDL and be associated with type 2 diabetes. In addition, the Pro12Ala variant of the PPARγ2 gene maybe correlated with abdominal obesity in type 2 diabetes. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB |
| WB:1:1,000-1:2,000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CIMT1 antibody GLM1 antibody NR1C3 antibody Nuclear receptor subfamily 1 group C member 3 antibody OTTHUMP00000185032 antibody OTTHUMP00000185036 antibody Peroxisome proliferator activated nuclear receptor gamma variant 1 antibody Peroxisome proliferator activated receptor gamma 1 antibody Peroxisome Proliferator Activated Receptor gamma antibody Peroxisome proliferator-activated receptor gamma antibody PPAR gamma antibody PPAR-gamma antibody PPARG antibody PPARG_HUMAN antibody PPARG1 antibody PPARG2 antibody PPARgamma antibody |
|---|---|
| Molecular Weight(MW) | 58 kDa |
| Cellular Localization | Nucleus, Cytoplasm. |
Application
Fig1: Western blot analysis of PPAR gamma on PC-12 cells lysates using anti-PPAR gamma antibody at 1/1,000 dilution.| Positive Control | PC-12. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
