Application
Fig1: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Parvalbumin antibody. Counter stained with hematoxylin.| Product Name | Parvalbumin [JM100-08] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | D22S749 antibody MGC116759 antibody Parvalbumin alpha antibody PRVA_HUMAN antibody PVALB antibody |
| Product description | Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:500-1:1,000 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | D22S749 antibody MGC116759 antibody Parvalbumin alpha antibody PRVA_HUMAN antibody PVALB antibody |
|---|---|
| Molecular Weight(MW) | 12 kDa |
| Cellular Localization | Cytoplasm, nucleus. |
| SwissProt ID | P20472 |
|---|
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Parvalbumin antibody. Counter stained with hematoxylin.| Positive Control | Human tonsil tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
