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Growth Hormone [JM108-09]

Catalog Number:OM628403
OM628403
Discount Price
OM628403-100ul
1~2 Week
100ul
OM628403-50ul
50ul
OM628403-20ul
20ul
1~2 Week
Product Profile
Product Name Growth Hormone [JM108-09]
Antibody Type Primary Antibodies
Product description Pituitary growth hormone (GH), also designated somatotropin, plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is secreted in a pulsatile pattern which is tightly controlled by the interplay of GH-releasing hormone (GHRH) and somatostatin (SRIF). GHRH and SRIF are the primary hypothalamic factors that determine GH secretion from the somatotroph and regulate GH synthesis and secretory reserve. GH output is also highly sensitive to feedback control by GH itself, as well as by insulin-like growth factor I. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Human growth hormone contains 191 amino acid residues with two disulfide bridges.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WB,IP,IHC
WB:1:1,000-1:5,000
IHC:1:50-1:200
Species Reactivity Human
Concentration 1mg/ml
Purification Unpurified
Target Information
Alternative Names gH antibody GH-N antibody GH1 antibody GHB5 antibody GHN antibody Growth hormone 1 antibody Growth hormone antibody Growth hormone B5 antibody Growth hormone
normal antibody Growth hormone
pituitary antibody HG1 antibody hGH-N antibody IGHD1B antibody Pituitary growth hormone antibody RNGHGP antibody SOMA_HUMAN antibody Somatotropin antibody
Molecular Weight(MW) 25 kDa
Cellular Localization Secreted.
Database Links
SwissProt ID P01241
Application

Application

Fig1: Western blot analysis of Growth Hormone on human placenta cells lysates using anti- Growth Hormone antibody at 1/500 dilution.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Growth Hormone antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Growth Hormone antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-Growth Hormone antibody. Counter stained with hematoxylin.
Positive Control Human placenta, human liver cancer tissue, human tonsil tissue, human breast tissue.
Application Notes WB:1:1,000-1:5,000
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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