Application
Fig1: Western blot analysis of L1CAM on different cells lysates using anti-L1CAM antibody at 1/500 dilution. Positive control： Line 1: Hela Line 2: human brainApplication
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-L1CAM antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human thyroid tissue using anti-L1CAM antibody. Counter stained with hematoxylin.| Product Name | L1CAM [JM11-05] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors, including neuroblastomas, rhabdomyosarcomas, Wilm's tumors, Ewing's sarcomas and some primitive myeloid malignancies. The NCAM-L1 adhesion molecule (CD171) plays an important role in axon guidance and cell migration in the nervous system. The presence of NCAM-L1 might contribute to tumor progression by promoting cell adhesion and migration and is known to be expressed by neurons, neuroblastomas and other malignant tumors. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB,IHC |
| WB:1:1,000-1:5,000 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | Antigen identified by monoclonal antibody R1 antibody CAML1 antibody CD171 antibody CD171 antigen antibody HSAS antibody HSAS1 antibody Hyd antibody L1 antibody L1 cell adhesion molecule antibody L1-NCAM antibody L1cam antibody L1CAM_HUMAN antibody MASA antibody MIC5 antibody N CAML1 antibody N-CAM-L1 antibody NCAM-L1 antibody NCAML1 antibody Nerve-growth factor-inducible large external glycoprotein antibody Neural cell adhesion molecule L1 antibody NILE antibody OTTHUMP00000025992 antibody S10 antibody SPG1 antibody |
|---|---|
| Molecular Weight(MW) | 85/250 kDa |
| Cellular Localization | Cell membrane. |
| SwissProt ID | P32004 |
|---|
Application
Fig1: Western blot analysis of L1CAM on different cells lysates using anti-L1CAM antibody at 1/500 dilution. Positive control： Line 1: Hela Line 2: human brain
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-L1CAM antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human thyroid tissue using anti-L1CAM antibody. Counter stained with hematoxylin.| Positive Control | Hela, human brain, human kidney tissue, human thyroid tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:5,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
