Application
Fig1: Western blot analysis of gamma Sarcoglycan on human skeletal muscle cells lysates using anti- gamma Sarcoglycan antibody at 1/500 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-gamma Sarcoglycan antibody. Counter stained with hematoxylin.| Product Name | gamma Sarcoglycan [JA11-57] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 35 kDa dystrophin associated glycoprotein antibody 35 kDa dystrophin-associated glycoprotein antibody 35DAG antibody 35kD dystrophin associated glycoprotein antibody 35kDa dystrophin-associated glycoprotein antibody A4 antibody DAGA4 antibody DMDA antibody DMDA1 antibody Gamma SG antibody Gamma-sarcoglycan antibody Gamma-SG antibody LGMD2C antibody MAM antibody MGC130048 antibody Sarcoglycan gamma antibody SCARMD2 antibody SCG3 antibody SGCG antibody SGCG_HUMAN antibody TYPE antibody |
| Product description | The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIPIHC |
| WB:1:500-1:2,000 IP:1:50-1:100 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | 35 kDa dystrophin associated glycoprotein antibody 35 kDa dystrophin-associated glycoprotein antibody 35DAG antibody 35kD dystrophin associated glycoprotein antibody 35kDa dystrophin-associated glycoprotein antibody A4 antibody DAGA4 antibody DMDA antibody DMDA1 antibody Gamma SG antibody Gamma-sarcoglycan antibody Gamma-SG antibody LGMD2C antibody MAM antibody MGC130048 antibody Sarcoglycan gamma antibody SCARMD2 antibody SCG3 antibody SGCG antibody SGCG_HUMAN antibody TYPE antibody |
|---|---|
| Molecular Weight(MW) | 32 kDa |
| Cellular Localization | Cell membrane. Cytoplasm. |
| SwissProt ID | Q13326 |
|---|
Application
Fig1: Western blot analysis of gamma Sarcoglycan on human skeletal muscle cells lysates using anti- gamma Sarcoglycan antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-gamma Sarcoglycan antibody. Counter stained with hematoxylin.| Positive Control | Human skeletal muscle cells lysates, mouse skeletal muscle tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IP:1:50-1:100 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
