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DR5 [JA03-38]
Catalog Number:OM628605
OM628605
Discount Price
OM628605-100ul
1~2 Week
100ul
OM628605-50ul
50ul
OM628605-20ul
20ul
1~2 Week
Product Profile
Product Name DR5 [JA03-38]
Antibody Type Primary Antibodies
Antigen Alias Fas like protein antibody Apoptosis inducing protein TRICK2A/2B antibody Apoptosis inducing receptor TRAIL R2 antibody CD262 antibody CD262 antigen antibody Cytotoxic TRAIL receptor 2 antibody Death domain containing receptor for TRAIL/Apo 2L antibody Death receptor 5 antibody DR5 antibody KILLER antibody KILLER/DR5 antibody OTTHUMP00000123492 antibody OTTHUMP00000123493 antibody p53 regulated DNA damage inducible cell death receptor(killer) antibody TNF related apoptosis inducing ligand receptor 2 antibody TNF-related apoptosis-inducing ligand receptor 2 antibody TNFRSF10B antibody TR10B_HUMAN antibody TRAIL R2 antibody TRAIL receptor 2 antibody TRAIL-R2 antibody TRAILR2 antibody TRICK2 antibody TRICK2A antibody TRICK2B antibody TRICKB antibody Tumor necrosis factor receptor like protein ZTNFR9 antibody Tumor necrosis factor receptor superfamily member 10B antibody Tumor necrosis factor receptor superfamily, member 10b antibody ZTNFR9 antibody
Product description Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes FAS antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the "death domain," that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including FAS, DR2 (or TRUNDD), DR3 (Death Receptor 3), DR4 and DR5. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. A non-death domain-containing receptor, designated decoy receptor (DcR1 or TRID), also specifically associates with TRAIL and may play a role in cellular resistance to apoptotic stimuli.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIPIHCFC
WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names Fas like protein antibody Apoptosis inducing protein TRICK2A/2B antibody Apoptosis inducing receptor TRAIL R2 antibody CD262 antibody CD262 antigen antibody Cytotoxic TRAIL receptor 2 antibody Death domain containing receptor for TRAIL/Apo 2L antibody Death receptor 5 antibody DR5 antibody KILLER antibody KILLER/DR5 antibody OTTHUMP00000123492 antibody OTTHUMP00000123493 antibody p53 regulated DNA damage inducible cell death receptor(killer) antibody TNF related apoptosis inducing ligand receptor 2 antibody TNF-related apoptosis-inducing ligand receptor 2 antibody TNFRSF10B antibody TR10B_HUMAN antibody TRAIL R2 antibody TRAIL receptor 2 antibody TRAIL-R2 antibody TRAILR2 antibody TRICK2 antibody TRICK2A antibody TRICK2B antibody TRICKB antibody Tumor necrosis factor receptor like protein ZTNFR9 antibody Tumor necrosis factor receptor superfamily member 10B antibody Tumor necrosis factor receptor superfamily
member 10b antibody ZTNFR9 antibody
Molecular Weight(MW) 48 kDa
Cellular Localization Membrane.
Database Links
SwissProt ID O14763
Application

Application

Fig6: Flow cytometric analysis of SW480 cells with DR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig6: Flow cytometric analysis of SW480 cells with DR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig6: Flow cytometric analysis of SW480 cells with DR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig6: Flow cytometric analysis of SW480 cells with DR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig6: Flow cytometric analysis of SW480 cells with DR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig6: Flow cytometric analysis of SW480 cells with DR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Positive Control HL-60, human tonsil tissue, human liver tissue, human colon cancer tissue, human placenta tissue, SW480.
Application Notes WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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