Application
Fig1: Immunohistochemical analysis of paraffin-embedded rat cartilage tissue using anti-Aggrecan antibody. Counter stained with hematoxylin.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Aggrecan antibody. Counter stained with hematoxylin.| Product Name | Aggrecan [JA40-23] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ACAN antibody AGC 1 antibody AGC1 antibody AGCAN antibody Aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) antibody Aggrecan 1 antibody Aggrecan core protein antibody Aggrecan proteoglycan antibody Aggrecan structural proteoglycan of cartilage antibody Aggrecan1 antibody ATEGQV antibody Cartilage specific proteoglycan core protein antibody Chondroitin sulfate proteoglycan 1 antibody Chondroitin sulfate proteoglycan 1 large aggregating proteoglycan antigen identified by monoclonal antibody A0122 antibody Chondroitin sulfate proteoglycan core protein 1 antibody CSPG 1 antibody CSPG1 antibody CSPGCP antibody JSCATE antibody Large aggregating proteoglycan antibody mcspg antibody mgsk16 antibody MSK 16 antibody MSK16 antibody SEDK antibody |
| Product description | The large chondroitin sulfate proteoglycan, aggrecan, is the predominant proteoglycan present in cartilage. Aggrecan is a member of the chondroitin sulphate proteoglycan family, which also includes versican/PG-M, neurocan and brevican. Aggrecan is a complex multidomain macromolecule that undergoes extensive processing and post-translational modification. Aggrecan in cartilage forms aggregates with hyaluronan and link protein, embedded in a collagen network. Aggrecan accounts for the compressive stiffness and resilience of the hyaline cartilage. Many forms of inflammatory arthritis are shown to be accompanied with aggrecan degradation and loss from the cartilage. Brevican is a brain proteoglycan of the aggrecan/versican/neurocan family. In the adult brain, the brevican core protein undergoes proteolytic cleavage and exists as a full-length form a carboxy-terminal fragment and an amino-terminal fragment. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | IHC |
| IHC:1:50-1:200 |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Alternative Names | ACAN antibody
AGC 1 antibody
AGC1 antibody
AGCAN antibody
Aggrecan 1 (chondroitin sulfate proteoglycan 1 large aggregating proteoglycan antigen identified by monoclonal antibody A0122) antibody Aggrecan 1 antibody Aggrecan core protein antibody Aggrecan proteoglycan antibody Aggrecan structural proteoglycan of cartilage antibody Aggrecan1 antibody ATEGQV antibody Cartilage specific proteoglycan core protein antibody Chondroitin sulfate proteoglycan 1 antibody Chondroitin sulfate proteoglycan 1 large aggregating proteoglycan antigen identified by monoclonal antibody A0122 antibody Chondroitin sulfate proteoglycan core protein 1 antibody CSPG 1 antibody CSPG1 antibody CSPGCP antibody JSCATE antibody Large aggregating proteoglycan antibody mcspg antibody mgsk16 antibody MSK 16 antibody MSK16 antibody SEDK antibody |
|---|---|
| Molecular Weight(MW) | 250/246/239 kDa |
| Cellular Localization | Secreted. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded rat cartilage tissue using anti-Aggrecan antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Aggrecan antibody. Counter stained with hematoxylin.| Positive Control | Rat cartilage tissue, human liver tissue. |
|---|---|
| Application Notes | IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
