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MEF2A [JA33-04]

Catalog Number:OM628611
OM628611
Discount Price
OM628611-100ul
1~2 Week
100ul
OM628611-50ul
50ul
OM628611-20ul
20ul
1~2 Week
Product Profile
Product Name MEF2A [JA33-04]
Antibody Type Primary Antibodies
Antigen Alias ADCAD1 antibody MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) antibody MEF2 antibody MEF2A antibody MEF2A_HUMAN antibody Myocyte enhancer factor 2A antibody Myocyte-specific enhancer factor 2A antibody RSRFC4 antibody RSRFC9 antibody Serum response factor like protein 1 antibody Serum response factor-like protein 1 antibody
Product description Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIHC
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names ADCAD1 antibody MADS box transcription enhancer factor 2
polypeptide A (myocyte enhancer factor 2A) antibody MEF2 antibody MEF2A antibody MEF2A_HUMAN antibody Myocyte enhancer factor 2A antibody Myocyte-specific enhancer factor 2A antibody RSRFC4 antibody RSRFC9 antibody Serum response factor like protein 1 antibody Serum response factor-like protein 1 antibody
Molecular Weight(MW) 54 kDa
Cellular Localization Nucleus.
Database Links
Application

Application

Fig1: Western blot analysis of MEF2A on rat spleen tissue lysate using anti-MEF2A antibody at 1/1,000 dilution.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-MEF2A antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-MEF2A antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-MEF2A antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded mouse cerebral cortex tissue using anti-MEF2A antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-MEF2A antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse hippocampus tissue using anti-MEF2A antibody. Counter stained with hematoxylin.
Positive Control Rat spleen tissue lysate, human tonsil tissue, human spleen tissue, mouse colon tissue, mouse cerebral cortex tissue, mouse spleen tissue, mouse hippocampus tissue.
Application Notes WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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