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SNAIL

Catalog Number:OM628619
OM628619
Discount Price
OM628619-100ul
1~2 Week
100ul
OM628619-50ul
50ul
OM628619-20ul
20ul
1~2 Week
Product Profile
Product Name SNAIL
Antibody Type Primary Antibodies
Antigen Alias dJ710H13.1 antibody Protein sna antibody Protein snail homolog 1 antibody Protein snail homolog antibody SLUGH2 antibody SNA antibody Sna protein antibody SNAH antibody SNAI antibody snai1 antibody SNAI1_HUMAN antibody Snail 1 homolog antibody Snail 1 zinc finger protein antibody SNAIL antibody Snail family transcriptional repressor 1 antibody Snail homolog 1 (Drosophila) antibody SNAIL, Drosophila, homolog of, 1 antibody SNAIL1 antibody Zinc finger protein SNAI1 antibody
Product description The Snail family of developmental regulatory proteins is a group of widely conserved zinc-finger proteins that regulate transcription and include the mammalian proteins SLUG, SNAI 1, the human homolog of Drosophila SNAIL, and Smuc. SNAI 1 and SLUG are expressed in placenta and adult heart, liver, and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna, each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. SLUG is implicated in the generation and migration of neural crest cells in human embryos and also contributes to limb bud development. In addition, SLUG also constitutes a cellular anti-apoptotic transcription factor that effectively prevents apoptosis in murine pro-B cells deprived of IL-3. The Snail-related gene from murine skeletal muscle cells, Smuc, is highly expressed in skeletal muscle and thymus and can, likewise, repress gene transcription. Smuc preferentially associates with CAGGTG and CACCTG E-box motifs (CANNTG) on DNA and involves the five putative DNA-binding zinc finger domains at the C-terminal region of Smuc.
Immunogen Peptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBICCIHC
WB:1:500-1:1,000
ICC:1:50-1:100
IHC:1:50-1:200
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Alternative Names dJ710H13.1 antibody Protein sna antibody Protein snail homolog 1 antibody Protein snail homolog antibody SLUGH2 antibody SNA antibody Sna protein antibody SNAH antibody SNAI antibody snai1 antibody SNAI1_HUMAN antibody Snail 1 homolog antibody Snail 1 zinc finger protein antibody SNAIL antibody Snail family transcriptional repressor 1 antibody Snail homolog 1 (Drosophila) antibody SNAIL
Drosophila
homolog of
1 antibody SNAIL1 antibody Zinc finger protein SNAI1 antibody
Molecular Weight(MW) 29 kDa, additional band 35 kDa
Cellular Localization Nucleus. Cytoplasm.
Database Links
SwissProt ID O95863 Q02085
Application

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-SNAI1 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-SNAI1 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-SNAI1 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-SNAI1 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-SNAI1 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-SNAI1 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-SNAI1 antibody. Counter stained with hematoxylin.
Positive Control Human kidney tissue, SiHa, K562, HUVEC, LOVO, human tonsil tissue, human liver cancer tissue, mouse testis tissue.
Application Notes WB:1:500-1:1,000
ICC:1:50-1:100
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
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