Application
Fig1: ICC staining USP36 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig2: ICC staining USP36 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig3: ICC staining USP36 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-USP36 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-USP36 antibody. Counter stained with hematoxylin.| Product Name | USP36 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Deubiquitinating enzyme 1 antibody Deubiquitinating enzyme 36 antibody DUB1 antibody FLJ12851 antibody KIAA1453 antibody Ubiquitin carboxyl-terminal hydrolase 36 antibody Ubiquitin specific peptidase 36 antibody Ubiquitin specific processing protease 36 antibody Ubiquitin thioesterase 36 antibody Ubiquitin thiolesterase 36 antibody Ubiquitin-specific-processing protease 36 antibody UBP36_HUMAN antibody Usp36 antibody |
| Product description | Ubiquitin-specific protease 36 is an enzyme that in humans is encoded by the USP36 gene. This gene encodes a member of the ubiquitin-specific protease family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the nucleoli and deubuquitinate nucleophosmin and fibrillarin. May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4). |
| Immunogen | Peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICCIHC |
| ICC:1:50-1:200 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Deubiquitinating enzyme 1 antibody Deubiquitinating enzyme 36 antibody DUB1 antibody FLJ12851 antibody KIAA1453 antibody Ubiquitin carboxyl-terminal hydrolase 36 antibody Ubiquitin specific peptidase 36 antibody Ubiquitin specific processing protease 36 antibody Ubiquitin thioesterase 36 antibody Ubiquitin thiolesterase 36 antibody Ubiquitin-specific-processing protease 36 antibody UBP36_HUMAN antibody Usp36 antibody |
|---|---|
| Molecular Weight(MW) | 123 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q9P275 |
|---|
Application
Fig1: ICC staining USP36 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig2: ICC staining USP36 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: ICC staining USP36 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-USP36 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-USP36 antibody. Counter stained with hematoxylin.| Positive Control | A549, Hela, LOVO, human liver cancer tissue, human spleen tissue. |
|---|---|
| Application Notes | ICC:1:50-1:200 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
