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CD71

Catalog Number:OM628638
OM628638
Discount Price
OM628638-100ul
1~2 Week
100ul
OM628638-50ul
50ul
OM628638-20ul
20ul
1~2 Week
Product Profile
Product Name CD71
Antibody Type Primary Antibodies
Antigen Alias CD 71 antibody CD71 antibody CD71 antigen antibody IMD46 antibody OTTHUMP00000208523 antibody OTTHUMP00000208524 antibody OTTHUMP00000208525 antibody p90 antibody sTfR antibody T9 antibody TFR 1 antibody TfR antibody TfR1 antibody TFR1_HUMAN antibody TFRC antibody TR antibody Transferrin receptor (p90 CD71) antibody Transferrin receptor protein 1, serum form antibody Trfr antibody
Product description CD71, also known as the transferrin receptor (TFR), is a type II membrane glycoprotein that exists as a disulfide-linked homodimer of two identical subunits. CD71 binds to two molecules of transferrin and a serum iron-transport protein, and directs the cellular uptake of iron via receptor-mediated endocytosis. CD71 is expressed, typically at high levels, on all proliferating cells, reticulocytes and erythroid precursors. It is not expressed on resting leukocytes, but is upregulated upon activation of lymphocytes, monocytes and macrophages. CD71 is also found on most dividing cells and on brain endothelium. A second transferrin receptor, TFR2, also mediates the uptake of transferrin-bound iron. TFR2 is a two-subunit homodimer and is highly expressed in liver as well as in hepatocytes and erythroid precursors. Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3), an iron overloading disorder predominant in Caucasians.
Immunogen Recombinant protein
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICCIHCFC
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Alternative Names CD 71 antibody CD71 antibody CD71 antigen antibody IMD46 antibody OTTHUMP00000208523 antibody OTTHUMP00000208524 antibody OTTHUMP00000208525 antibody p90 antibody sTfR antibody T9 antibody TFR 1 antibody TfR antibody TfR1 antibody TFR1_HUMAN antibody TFRC antibody TR antibody Transferrin receptor (p90 CD71) antibody Transferrin receptor protein 1
serum form antibody Trfr antibody
Molecular Weight(MW) 84 kDa
Cellular Localization Secreted and Cell membrane. Melanosome.
Database Links
SwissProt ID P02786 Q62351
Application

Application

Fig8: Flow cytometric analysis of HL-60 cells with CD71 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of HL-60 cells with CD71 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of HL-60 cells with CD71 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of HL-60 cells with CD71 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of HL-60 cells with CD71 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of HL-60 cells with CD71 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of HL-60 cells with CD71 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Application

Fig8: Flow cytometric analysis of HL-60 cells with CD71 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.
Positive Control A549, MCF-7, PC-3M, human kidney tissue, human placenta tissue, mouse brain tissue, mouse kidney tissue, HL-60.
Application Notes ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
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