Application
Fig1: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-OGG1 antibody. Counter stained with hematoxylin.| Product Name | OGG1 [JA18-13] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 8 hydroxyguanine DNA glycosylase antibody 8 oxoguanine DNA glycosylase 1 antibody 8 oxoguanine DNA glycosylase antibody AP lyase antibody DNA (apurinic or apyrimidinic site) lyase antibody DNA apurinic or apyrimidinic site lyase antibody DNA lyase antibody DNA-(apurinic or apyrimidinic site) lyase antibody HMMH antibody HOGG 1 antibody HOGG1 antibody MMH antibody MUTM antibody N glycosylase antibody Ogg 1 antibody Ogg1 antibody OGG1_HUMAN antibody OGH 1 antibody OGH1 antibody |
| Product description | DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | 8 hydroxyguanine DNA glycosylase antibody 8 oxoguanine DNA glycosylase 1 antibody 8 oxoguanine DNA glycosylase antibody AP lyase antibody DNA (apurinic or apyrimidinic site) lyase antibody DNA apurinic or apyrimidinic site lyase antibody DNA lyase antibody DNA-(apurinic or apyrimidinic site) lyase antibody HMMH antibody HOGG 1 antibody HOGG1 antibody MMH antibody MUTM antibody N glycosylase antibody Ogg 1 antibody Ogg1 antibody OGG1_HUMAN antibody OGH 1 antibody OGH1 antibody |
|---|---|
| Molecular Weight(MW) | 39 kDa |
| Cellular Localization | Mitochondrion. Nucleus. |
| SwissProt ID | O15527 |
|---|
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-OGG1 antibody. Counter stained with hematoxylin.| Positive Control | Human kidney tissue. |
|---|---|
| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
