Application
Fig1: Western blot analysis of 5HT2C Receptor on A431 (1) AND K562 (2) lysates using anti-5HT2C Receptor antibody at 1/1,000 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-5HT2C Receptor antibody. Counter stained with hematoxylin.| Product Name | 5HT2C Receptor [JA31-31] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 5 Hydroxytryptamine 2C receptor antibody 5-HT-1C antibody 5-ht-1c receptor antibody 5-HT-2C antibody 5-HT1C antibody 5-HT2C antibody 5-HTR2C antibody 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antibody 5-hydroxytryptamine receptor 1C antibody 5-hydroxytryptamine receptor 2C antibody 5HT1C antibody 5HT2C antibody 5HT2C_HUMAN antibody 5HTR2C antibody 5Hydroxytryptamine 2C receptor antibody Htr1c antibody HTR2C antibody serotonin 1c receptor antibody serotonin 2c receptor antibody Serotonin 5-HT-2C receptor antibody Serotonin receptor 2C antibody |
| Product description | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 5 Hydroxytryptamine 2C receptor antibody
5-HT-1C antibody
5-ht-1c receptor antibody
5-HT-2C antibody
5-HT1C antibody
5-HT2C antibody
5-HTR2C antibody
5-hydroxytryptamine (serotonin) receptor 2C G protein-coupled antibody 5-hydroxytryptamine receptor 1C antibody 5-hydroxytryptamine receptor 2C antibody 5HT1C antibody 5HT2C antibody 5HT2C_HUMAN antibody 5HTR2C antibody 5Hydroxytryptamine 2C receptor antibody Htr1c antibody HTR2C antibody serotonin 1c receptor antibody serotonin 2c receptor antibody Serotonin 5-HT-2C receptor antibody Serotonin receptor 2C antibody |
|---|---|
| Molecular Weight(MW) | 70 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Membrane. Cell membrane.? |
Application
Fig1: Western blot analysis of 5HT2C Receptor on A431 (1) AND K562 (2) lysates using anti-5HT2C Receptor antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-5HT2C Receptor antibody. Counter stained with hematoxylin.| Positive Control | A431, K562, mouse brain tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
