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IDH2 [JA55-31]

Catalog Number:OM628663
OM628663
Discount Price
OM628663-100ul
1~2 Week
100ul
OM628663-50ul
50ul
OM628663-20ul
20ul
1~2 Week
Product Profile
Product Name IDH2 [JA55-31]
Antibody Type Primary Antibodies
Antigen Alias D2HGA2 antibody ICD-M antibody IDH antibody IDH2 antibody IDHM antibody IDHP_HUMAN antibody IDP antibody IDPM antibody Isocitrate dehydrogenase [NADP], mitochondrial antibody Isocitrate dehydrogenase 2 (NADP+), mitochondrial antibody mNADP-IDH antibody NADP(+)-specific ICDH antibody Oxalosuccinate decarboxylase antibody
Product description IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452 amino acid enzyme encoded by the human gene IDH2. IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions. IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria. It is believed to play a role in intermediary metabolism and energy production. IDH2 also tightly associates with the pyruvate dehydrogenase complex. IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit.
Immunogen recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIHCFC
WB:1:500-1:2,000
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names D2HGA2 antibody ICD-M antibody IDH antibody IDH2 antibody IDHM antibody IDHP_HUMAN antibody IDP antibody IDPM antibody Isocitrate dehydrogenase [NADP]
mitochondrial antibody Isocitrate dehydrogenase 2 (NADP+)
mitochondrial antibody mNADP-IDH antibody NADP(+)-specific ICDH antibody Oxalosuccinate decarboxylase antibody
Molecular Weight(MW) 45 kDa
Cellular Localization Mitochondrion.
Database Links
Application

Application

Fig7: Flow cytometric analysis of MCF-7 cells with IDH2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig7: Flow cytometric analysis of MCF-7 cells with IDH2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig7: Flow cytometric analysis of MCF-7 cells with IDH2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig7: Flow cytometric analysis of MCF-7 cells with IDH2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig7: Flow cytometric analysis of MCF-7 cells with IDH2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig7: Flow cytometric analysis of MCF-7 cells with IDH2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig7: Flow cytometric analysis of MCF-7 cells with IDH2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Positive Control 293T, mouse heart tissue lysate, rat heart tissue lysate, human liver tissue, human prostate tissue, MCF-7.
Application Notes WB:1:500-1:2,000
IHC:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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