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TLR4
Catalog Number:OM628670
OM628670
Discount Price
OM628670-100ul
1~2 Week
100ul
OM628670-50ul
50ul
OM628670-20ul
20ul
1~2 Week
Product Profile
Product Name TLR4
Antibody Type Primary Antibodies
Antigen Alias ARMD10 antibody CD284 antibody CD284 antigen antibody Homolog of Drosophila toll antibody hToll antibody TLR 4 antibody TLR4 antibody TLR4_HUMAN antibody TOLL antibody Toll like receptor 4 antibody Toll-like receptor 4 antibody
Product description Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated toll-like receptors (TLR). Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo and participate in the host immunity. The TLR family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll / IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macro-phages, and TLR6 is highly homologous to TLR1, sharing greater than 65% sequence identity, and, like other members of TLR family, it induces NFkB signaling upon activation.
Immunogen Peptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICCIHCFCWB
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
WB:1:500
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names ARMD10 antibody CD284 antibody CD284 antigen antibody Homolog of Drosophila toll antibody hToll antibody TLR 4 antibody TLR4 antibody TLR4_HUMAN antibody TOLL antibody Toll like receptor 4 antibody Toll-like receptor 4 antibody
Molecular Weight(MW) 96/91/73 kDa
Cellular Localization Cell membrane.
Database Links
Application

Application

Fig8: Flow cytometric analysis of Jurkat cells with TLR4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig8: Flow cytometric analysis of Jurkat cells with TLR4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig8: Flow cytometric analysis of Jurkat cells with TLR4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig8: Flow cytometric analysis of Jurkat cells with TLR4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig8: Flow cytometric analysis of Jurkat cells with TLR4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig8: Flow cytometric analysis of Jurkat cells with TLR4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig8: Flow cytometric analysis of Jurkat cells with TLR4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig8: Flow cytometric analysis of Jurkat cells with TLR4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Positive Control Hela, HUVEC, PMVEC, rat kidney tissue, human skin tissue, human spleen tissue, mouse colon tissue, Jurkat.
Application Notes ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
WB:1:500
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
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