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NaV1.7
Catalog Number:OM628672
OM628672
Discount Price
OM628672-100ul
1~2 Week
100ul
OM628672-50ul
50ul
OM628672-20ul
20ul
1~2 Week
Product Profile
Product Name NaV1.7
Antibody Type Primary Antibodies
Antigen Alias ETHA antibody GEFSP7 antibody hNE Na antibody hNE-Na antibody hNENa antibody NE NA antibody NENA antibody Neuroendocrine sodium channel antibody Peripheral sodium channel 1 antibody PN1 antibody Scn9a antibody SCN9A_HUMAN antibody Sodium channel protein type 9 subunit alpha antibody Sodium channel protein type IX subunit alpha antibody Sodium channel voltage gated type IX alpha antibody Sodium channel voltage gated type IX alpha polypeptide antibody Sodium channel voltage gated type IX alpha subunit antibody Voltage gated sodium channel alpha subunit Nav1.7 antibody Voltage gated sodium channel subunit alpha Nav1 antibody Voltage-gated sodium channel subunit alpha Nav1.7 antibody
Product description Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na+ channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.
Immunogen Peptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICCIHCFC
ICC:1:50-1:200
ICC:1:50-1:200
FC:1:50-1:100
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names ETHA antibody GEFSP7 antibody hNE Na antibody hNE-Na antibody hNENa antibody NE NA antibody NENA antibody Neuroendocrine sodium channel antibody Peripheral sodium channel 1 antibody PN1 antibody Scn9a antibody SCN9A_HUMAN antibody Sodium channel protein type 9 subunit alpha antibody Sodium channel protein type IX subunit alpha antibody Sodium channel voltage gated type IX alpha antibody Sodium channel voltage gated type IX alpha polypeptide antibody Sodium channel voltage gated type IX alpha subunit antibody Voltage gated sodium channel alpha subunit Nav1.7 antibody Voltage gated sodium channel subunit alpha Nav1 antibody Voltage-gated sodium channel subunit alpha Nav1.7 antibody
Molecular Weight(MW) 226 kDa
Cellular Localization Cell membrane. Cell projection.
Database Links
SwissProt ID Q15858
Application

Application

Fig1: ICC staining NaV1.7 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig2: ICC staining NaV1.7 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: ICC staining NaV1.7 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-NaV1.7 beta antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-NaV1.7 beta antibody. Counter stained with hematoxylin.

Application

Fig6: Flow cytometric analysis of SH-SY5Y cells with NaV1.7 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Positive Control A549, Hela, SH-SY5Y, human liver cancer tissue, mouse colon tissue.
Application Notes ICC:1:50-1:200
ICC:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
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