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PLGF [JA63-15]

Catalog Number:OM628673
OM628673
Discount Price
OM628673-100ul
1~2 Week
100ul
OM628673-50ul
50ul
OM628673-20ul
20ul
1~2 Week
Product Profile
Product Name PLGF [JA63-15]
Antibody Type Primary Antibodies
Antigen Alias D12S1900 antibody Pgf antibody PGFL antibody PIGF antibody Placenta growth factor antibody Placental growth factor antibody Placental growth factor, vascular endothelial growth factor related protein antibody PlGF 2 antibody PlGF antibody PLGF_HUMAN antibody PlGF2 antibody SHGC 10760 antibody
Product description he onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF). Like VEGF, several PlGF variants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PlGF signaling. While VEGF homodimers and VEGF/PlGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PlGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PlGF. VEGF and PlGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICCIHC
WB:1:500~1:2000
ICC:1:200~1:500
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names D12S1900 antibody Pgf antibody PGFL antibody PIGF antibody Placenta growth factor antibody Placental growth factor antibody Placental growth factor
vascular endothelial growth factor related protein antibody PlGF 2 antibody PlGF antibody PLGF_HUMAN antibody PlGF2 antibody SHGC 10760 antibody
Molecular Weight(MW) 50 kDa
Cellular Localization Secreted.
Database Links
SwissProt ID P49763
Application

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse orchis tissue using anti-PLGF antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse orchis tissue using anti-PLGF antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse orchis tissue using anti-PLGF antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse orchis tissue using anti-PLGF antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse orchis tissue using anti-PLGF antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse orchis tissue using anti-PLGF antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded mouse orchis tissue using anti-PLGF antibody. Counter stained with hematoxylin.
Positive Control SH-SY5Y cell lysate, HepG2, MCF-7, rat kidney tissue, human colon cancer tissue, mouse orchis tissue, human liver cancer tissue.
Application Notes WB:1:500~1:2000
ICC:1:200~1:500
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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