Application
Fig4: Flow cytometric analysis of MCF-7 cells with SOD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.Application
Fig4: Flow cytometric analysis of MCF-7 cells with SOD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.Application
Fig4: Flow cytometric analysis of MCF-7 cells with SOD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.Application
Fig4: Flow cytometric analysis of MCF-7 cells with SOD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.| Product Name | SOD1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ALS antibody ALS1 antibody Amyotrophic lateral sclerosis 1 adult antibody Cu/Zn SOD antibody Cu/Zn superoxide dismutase antibody Epididymis secretory protein Li 44 antibody HEL S 44 antibody Homodimer antibody hSod1 antibody Indophenoloxidase A antibody IPOA antibody Mn superoxide dismutase antibody SOD antibody SOD soluble antibody SOD1 antibody SOD2 antibody SODC antibody SODC_HUMAN antibody Superoxide dismutase [Cu-Zn] antibody Superoxide dismutase 1 antibody Superoxide dismutase 1 soluble antibody Superoxide dismutase Cu Zn antibody Superoxide dismutase cystolic antibody |
| Product description | Cu-Zn superoxide dismutase-1 (SOD-1) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. SOD-1 is ubiquitously expressed in somatic cells and functions as a homodimer. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the loss of spinal motor neurons, Down syndrome and Alzheimer's disease. In familial ALS, several mutations in SOD-1 predominate, resulting in the loss of zinc binding, the loss of scavenging activity of SOD-1, and correlate with an increase in neurotoxicity and motor neuron death. |
| Immunogen | Recombinant protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCFC |
| WB:1:500 ICC:1:500-1:2,000 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ALS antibody ALS1 antibody Amyotrophic lateral sclerosis 1 adult antibody Cu/Zn SOD antibody Cu/Zn superoxide dismutase antibody Epididymis secretory protein Li 44 antibody HEL S 44 antibody Homodimer antibody hSod1 antibody Indophenoloxidase A antibody IPOA antibody Mn superoxide dismutase antibody SOD antibody SOD soluble antibody SOD1 antibody SOD2 antibody SODC antibody SODC_HUMAN antibody Superoxide dismutase [Cu-Zn] antibody Superoxide dismutase 1 antibody Superoxide dismutase 1 soluble antibody Superoxide dismutase Cu Zn antibody Superoxide dismutase cystolic antibody |
|---|---|
| Molecular Weight(MW) | 16 kDa |
| Cellular Localization | Mitochondrion. Nucleus. |
Application
Fig4: Flow cytometric analysis of MCF-7 cells with SOD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Application
Fig4: Flow cytometric analysis of MCF-7 cells with SOD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Application
Fig4: Flow cytometric analysis of MCF-7 cells with SOD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Application
Fig4: Flow cytometric analysis of MCF-7 cells with SOD1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.| Positive Control | A549, HepG2, LOVO, rat testis tissue, human liver tissue, human kidney tissue, mouse brain tissue,MCF-7. |
|---|---|
| Application Notes | WB:1:500 ICC:1:500-1:2,000 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
