Application
Fig2: Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CD1a antibody. Counter stained with hematoxylin.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CD1a antibody. Counter stained with hematoxylin.| Product Name | CD1a [JM21-33] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD 1a antibody CD1 antibody CD1a antibody CD1A Antigen antibody CD1A antigen, a polypeptide antibody CD1a molecule antibody CD1A_HUMAN antibody cluster of differentiation 1 A antibody cortical thymocyte antigen CD1A antibody differentiation antigen CD1 alpha 3 antibody epidermal dendritic cell marker CD1a antibody FCB 6 antibody FCB6 antibody HTA 1 antibody HTA1 antibody hTa1 thymocyte antigen antibody OTTHUMP00000018907 antibody R 4 antibody R4 antibody T 6 antibody T-cell surface antigen T6/Leu-6 antibody T-cell surface glycoprotein CD1a antibody T6 antibody |
| Product description | The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with β-2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CD 1a antibody
CD1 antibody
CD1a antibody
CD1A Antigen antibody
CD1A antigen a polypeptide antibody CD1a molecule antibody CD1A_HUMAN antibody cluster of differentiation 1 A antibody cortical thymocyte antigen CD1A antibody differentiation antigen CD1 alpha 3 antibody epidermal dendritic cell marker CD1a antibody FCB 6 antibody FCB6 antibody HTA 1 antibody HTA1 antibody hTa1 thymocyte antigen antibody OTTHUMP00000018907 antibody R 4 antibody R4 antibody T 6 antibody T-cell surface antigen T6/Leu-6 antibody T-cell surface glycoprotein CD1a antibody T6 antibody |
|---|---|
| Molecular Weight(MW) | 37 kDa |
| Cellular Localization | Cell membrane. Endosome membrane. |
| SwissProt ID | P06126 |
|---|
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CD1a antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CD1a antibody. Counter stained with hematoxylin.| Positive Control | Human skin tissue, human tonsil tissue. |
|---|---|
| Application Notes | WB:1:500 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
