Application
Fig1: Western blot analysis of LOX1 on siHa cell lysate using anti-LOX1 antibody at 1/100 dilution.Application
Fig2: ICC staining LOX1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig3: ICC staining LOX1 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LOX1 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-LOX1 antibody. Counter stained with hematoxylin.Application
Fig6: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-LOX1 antibody. Counter stained with hematoxylin.Application
Fig7: Flow cytometric analysis of LOVO cells with LOX1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.Application
Fig8: Western blot analysis of LOX1 on human lung tissue lysate using anti-LOX1 antibody at 1/500 dilution.| Product Name | LOX-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C-type lectin domain family 8 member A antibody CLEC8A antibody hLOX 1 antibody hLOX-1 antibody Lectin like oxidized LDL receptor 1 antibody Lectin like oxLDL receptor 1 antibody Lectin type oxidized LDL receptor 1 antibody Lectin-like oxidized LDL receptor 1 antibody Lectin-like oxLDL receptor 1 antibody Lectin-type oxidized LDL receptor 1 antibody low density lipoprotein oxidized, receptor 1 antibody LOX-1 antibody LOXIN antibody Olr1 antibody OLR1_HUMAN antibody Ox LDL receptor 1 antibody Ox-LDL receptor 1 antibody Oxidised low density lipoprotein (lectin like) receptor 1 antibody Oxidized low density lipoprotein receptor 1 antibody Oxidized low density lipoprotein receptor 1 soluble form antibody Oxidized low-density lipoprotein receptor 1 antibody SCARE1 antibody Scavenger receptor class E, member 1 antibody SLOX1 antibody soluble form antibody SR-EI antibody |
| Product description | The oxidized low density lipoprotein (lectin-like) receptor-1, Ox-LDL R-1, is a type II membrane protein that is a member of the C-type lectin family and acts as a cell-surface receptor for oxidized low density lipoprotein (Ox-LDL). Ox-LDL plays a role in early atherosclerosis, which includes the transformation of monocyte-derived macrophages to foam cells in atherosclerotic lesions. The binding of Ox-LDL to Ox-LDL R-1 may also trigger the activation of the NFkB signal transduction pathway. Ox-LDL R-1, also designated scavenger receptor class E, member 1 (SCARE1); lectin-type oxidized LDL receptor 1 (LOX-1); and CLEC8A), is expressed by vascular endothelial cells, smooth muscle cells and macrophages. It is expressed endogenously as a precursor form with N-linked high mannose carbohydrate chains and as a mature form due to further glycosylation. The N-linked glycosylation of Ox-LDL R-1 appears to be necessary for adequate transportation to the cell surface and efficient ligand binding. |
| Immunogen | Recombinant protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFC |
| WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | C-type lectin domain family 8 member A antibody
CLEC8A antibody
hLOX 1 antibody
hLOX-1 antibody
Lectin like oxidized LDL receptor 1 antibody
Lectin like oxLDL receptor 1 antibody
Lectin type oxidized LDL receptor 1 antibody
Lectin-like oxidized LDL receptor 1 antibody
Lectin-like oxLDL receptor 1 antibody
Lectin-type oxidized LDL receptor 1 antibody
low density lipoprotein oxidized receptor 1 antibody LOX-1 antibody LOXIN antibody Olr1 antibody OLR1_HUMAN antibody Ox LDL receptor 1 antibody Ox-LDL receptor 1 antibody Oxidised low density lipoprotein (lectin like) receptor 1 antibody Oxidized low density lipoprotein receptor 1 antibody Oxidized low density lipoprotein receptor 1 soluble form antibody Oxidized low-density lipoprotein receptor 1 antibody SCARE1 antibody Scavenger receptor class E member 1 antibody SLOX1 antibody soluble form antibody SR-EI antibody |
|---|---|
| Molecular Weight(MW) | 31 kDa |
| Cellular Localization | Cell membrane. Secreted. |
Application
Fig1: Western blot analysis of LOX1 on siHa cell lysate using anti-LOX1 antibody at 1/100 dilution.
Application
Fig2: ICC staining LOX1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: ICC staining LOX1 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LOX1 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-LOX1 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-LOX1 antibody. Counter stained with hematoxylin.
Application
Fig7: Flow cytometric analysis of LOVO cells with LOX1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Application
Fig8: Western blot analysis of LOX1 on human lung tissue lysate using anti-LOX1 antibody at 1/500 dilution.| Positive Control | siHa, Hela, LOVO, human lung tissue lysate, human kidney tissue, human placenta tissue, mouse brain tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
