Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Product Name | BMAL1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARNT like protein 1 brain and muscle antibody Arntl antibody Aryl hydrocarbon receptor nuclear translocator like antibody Aryl hydrocarbon receptor nuclear translocator like protein 1 antibody Aryl hydrocarbon receptor nuclear translocator-like protein 1 antibody Basic helix loop helix PAS orphan MOP3 antibody Basic helix loop helix PAS protein MOP3 antibody Basic-helix-loop-helix-PAS protein MOP3 antibody bHLH PAS protein JAP3 antibody bHLH-PAS protein JAP3 antibody bHLHe5 antibody BMAL 1 antibody BMAL1_HUMAN antibody BMAL1c antibody Brain and muscle ARNT like 1 antibody Brain and muscle ARNT-like 1 antibody CG8727 PA antibody Class E basic helix-loop-helix protein 5 antibody cycle antibody JAP 3 antibody JAP3 antibody Member of PAS protein 3 antibody Member of PAS superfamily 3 antibody MGC47515 antibody MOP 3 antibody MOP3 antibody PAS domain-containing protein 3 antibody PASD 3 antibody PASD3 antibody TIC antibody |
| Product description | BMAL1, ARNTL2 (aryl hydrocarbon receptor nuclear translocator-like 2) is a basic Helix-Loop-Helix-Per-Arnt-Sim (bHLH-PAS) transcription factor. ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1. The NPAS2-ARNTL/BMAL1 heterodimer positively regulates the expression of MAOA, F7 and LDHA and modulates the circadian rhythm of daytime contrast sensitivity by regulating the rhythmic expression of adenylate cyclase type 1 (ADCY1) in the retina. The CLOCK-ARNTL/BMAL1 heterodimer also recognizes the non-canonical E-box motifs 5'-AACGTGA-3' and 5'-CATGTGA-3'. Essential for the rhythmic interaction of CLOCK with ASS1 and plays a critical role in positively regulating CLOCK-mediated acetylation of ASS1. |
| Immunogen | Recombinant protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFC |
| WB:1:500-2,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ARNT like protein 1 brain and muscle antibody Arntl antibody Aryl hydrocarbon receptor nuclear translocator like antibody Aryl hydrocarbon receptor nuclear translocator like protein 1 antibody Aryl hydrocarbon receptor nuclear translocator-like protein 1 antibody Basic helix loop helix PAS orphan MOP3 antibody Basic helix loop helix PAS protein MOP3 antibody Basic-helix-loop-helix-PAS protein MOP3 antibody bHLH PAS protein JAP3 antibody bHLH-PAS protein JAP3 antibody bHLHe5 antibody BMAL 1 antibody BMAL1_HUMAN antibody BMAL1c antibody Brain and muscle ARNT like 1 antibody Brain and muscle ARNT-like 1 antibody CG8727 PA antibody Class E basic helix-loop-helix protein 5 antibody cycle antibody JAP 3 antibody JAP3 antibody Member of PAS protein 3 antibody Member of PAS superfamily 3 antibody MGC47515 antibody MOP 3 antibody MOP3 antibody PAS domain-containing protein 3 antibody PASD 3 antibody PASD3 antibody TIC antibody |
|---|---|
| Molecular Weight(MW) | 68 kDa |
| Cellular Localization | Cytoplasm, Nucleus. |
Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SHSY5Y cells with BMAL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Positive Control | SYSH5Y, A549, MCF-7, human liver cancer tissue, human prostate tissue, mouse brain tissue, mouse prostate tissue, rat brain tissue. |
|---|---|
| Application Notes | WB:1:500-2,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
